FGFBP1 - fibroblast growth factor binding protein 1 Gene

中文名称：成纤维细胞生长因子结合蛋白 1

种属: Homo sapiens

同用名: FGFBP; HBP17; FGF-BP; FGF-BP1; FGFBP-1

关于 FGFBP1

功能概要

该基因编码分泌的成纤维细胞生长因子载体蛋白。编码的蛋白质通过与成纤维细胞生长因子结合并增强它们对靶细胞的生物学效应，在细胞增殖、分化和迁移中发挥关键作用。编码的蛋白质也可能作为血管生成开关分子在肿瘤生长中发挥作用，并且该基因的表达与几种类型的癌症有关，包括胰腺癌和结直肠腺癌。该基因的假基因也位于 4 号染色体的短臂上。[RefSeq 提供，2011 年 11 月]

This gene encodes a secreted Fibroblast Growth Factor carrier protein. The encoded protein plays a critical role in cell proliferation, differentiation and migration by binding to fibroblast growth factors and potentiating their biological effects on target cells. The encoded protein may also play a role in tumor growth as an angiogenic switch molecule, and expression of this gene has been associated with several types of Cancer including pancreatic and colorectal adenocarcinoma. A pseudogene of this gene is also located on the short arm of chromosome 4. [provided by RefSeq, Nov 2011]