2. Neuronal Signaling
  3. Beta-secretase Cholinesterase (ChE)
  4. hAChE/hBACE-1-IN-3

hAChE/hBACE-1-IN-3 (Compound 23a) 是 hAChE 和 hBACE-1 的混合型抑制剂，IC50 值分别为 0.32 μM 和 0.39 μM，Ki 值分别为 0.26 μM 和 0.46 μM。hAChE/hBACE-1-IN-3 能透过血脑屏障。

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hAChE/hBACE-1-IN-3 Chemical Structure

hAChE/hBACE-1-IN-3 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
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hAChE/hBACE-1-IN-3 相关抗体

Top Publications Citing Use of Products

查看 Beta-secretase 亚型特异性产品:

查看所有亚型
BACE1 BACE2

查看 Cholinesterase (ChE) 亚型特异性产品:

查看所有亚型
AChE BChE

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

hAChE/hBACE-1-IN-3 (Compound 23a) is a mixed-type inhibitor of hAChE and hBACE-1 with IC50 values of 0.32 μM and 0.39 μM, respectively, Ki values of 0.26 μM and 0.46 μM, respectively. hAChE/hBACE-1-IN-3 can penetrate the blood-brain barrier[1].

IC50 & Target

IC50: 0.32 μM (hAChE), 0.39 μM (hBACE-1)[1]
分子量

421.53

Formula

C25H31N3O3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

hAChE/hBACE-1-IN-3 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

hAChE/hBACE-1-IN-3Beta-secretaseCholinesterase (ChE)BACEβ-SecretasehAChE/hBACE-1 InhibitorNeurological DiseaseAlzheimer’s DiseaseInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-162127
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