2. Neuronal Signaling Stem Cell/Wnt PI3K/Akt/mTOR
  3. Cholinesterase (ChE) GSK-3
  4. hAChE/hBuChE/GSK-3β-IN-1

hAChE/hBuChE/GSK-3β-IN-1 (Compound 6c) 是一种能透过血脑屏障的多靶点抗阿尔茨海默症的化合物。hAChE/hBuChE/GSK-3β-IN-1 是 hAChE (IC50: 28.88 nM)、hBuChE (IC50: 131.90 nM) 和 GSK-3β (IC50: 51.42 nM) 的抑制剂。hAChE/hBuChE/GSK-3β-IN-1 是 tau 蛋白和 Aβ 蛋白聚集的抑制剂。

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hAChE/hBuChE/GSK-3β-IN-1 Chemical Structure

hAChE/hBuChE/GSK-3β-IN-1 Chemical Structure

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规格 是否有货
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Customer Review

hAChE/hBuChE/GSK-3β-IN-1 相关抗体

Top Publications Citing Use of Products

查看 Cholinesterase (ChE) 亚型特异性产品:

查看所有亚型
AChE BChE

查看 GSK-3 亚型特异性产品:

查看所有亚型
GSK-3 GSK-3α GSK-3β

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

hAChE/hBuChE/GSK-3β-IN-1 (Compound 6c) is a BBB-penatrable and multi-target anti-Alzheimer's disease compound. hAChE/hBuChE/GSK-3β-IN-1 is the inhibitors of hAChE (IC50: 28.88 nM), hBuChE (IC50: 131.90 nM) and GSK-3β (IC50: 51.42 nM). hAChE/hBuChE/GSK-3β-IN-1 is the tau and Aβ protein aggregation inhibitors[1].

IC50 & Target[1]

hAChE

28.88 nM (IC50)

hBCHE

131.90 nM (IC50)

GSK-3β

51.42 nM (IC50)

分子量

321.33

Formula

C19H15NO4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

hAChE/hBuChE/GSK-3β-IN-1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

hAChE/hBuChE/GSK-3β-IN-1Cholinesterase (ChE)GSK-3Glycogen synthase kinase-3Glycogen synthase kinase 3Inhibitorinhibitorinhibit

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