2. Neuronal Signaling
  3. Cholinesterase (ChE) Tau Protein
  4. hAChE-IN-2

hAChE-IN-2是一种有效的 hAChE 抑制剂，IC50 值为 0.71 μM。hAChE-IN-2 还可以抑制 tau 寡聚化，EC50 为 2.21 μM。hAChE-IN-2 具有神经保护活性。

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hAChE-IN-2 Chemical Structure

hAChE-IN-2 Chemical Structure

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hAChE-IN-2 相关抗体

Top Publications Citing Use of Products

查看 Cholinesterase (ChE) 亚型特异性产品:

查看所有亚型
AChE BChE

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

hAChE-IN-2 is a potent hAChE inhibitor, with an IC50 of 0.71 μM. hAChE-IN-2 can also inhibits tau-oligomerization, with an EC50 of 2.21 μM. hAChE-IN-2 exhibits neuroprotective activity[1].

IC50 & Target[1]

hAChE

0.71 μM (IC50)

体外研究
(In Vitro)

hAChE-IN-2 (compound 21) (1-10 μM) 在转染 WT tau 的 SH-SY5Y 细胞中显示出神经保护活性[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

hAChE-IN-2 相关抗体:
分子量

394.44

Formula

C22H23FN4O2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

hAChE-IN-2 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

hAChE-IN-2Cholinesterase (ChE)Tau ProteinhAChEtauoligomerizationneuroprotectiveInhibitorinhibitorinhibit

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目录号：
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