2. Membrane Transporter/Ion Channel
  3. Sodium Channel
  4. Hainantoxin-III

Jingzhaotoxin-V 是一种抑制非洲爪蟾卵母细胞钾电流的多肽，IC50 值为 604.2 nM。 Jingzhaotoxin-V 还可抑制大鼠背根神经节神经元中的河豚毒素抗性和河豚毒素敏感钠电流，IC50 值分别为 27.6 和 30.2 nM[1 ]。

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Custom Peptide Synthesis

Hainantoxin-III Chemical Structure

Hainantoxin-III Chemical Structure

CAS No. : 1809149-40-3

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Hainantoxin-III 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Jingzhaotoxin-V is a peptide that inhibits potassium currents in Xenopus laevis oocytes with an IC50 value of 604.2 nM. Jingzhaotoxin-V also inhibits tetrodotoxin-resistant and tetrodotoxin-sensitive sodium currents in rat dorsal root ganglion neurons with IC50 values of 27.6 and 30.2 nM, respectively[1].

IC50 & Target

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分子量

3608.12

Formula

C154H228N44O45S6
CAS 号
Sequence

Gly-Cys-Lys-Gly-Phe-Gly-Asp-Ser-Cys-Thr-Pro-Gly-Lys-Asn-Glu-Cys-Cys-Pro-Asn-Tyr-Ala-Cys-Ser-Ser-Lys-His-Lys-Trp-Cys-Lys-Val-Tyr-Leu-NH2 (Disulfide bonds: Cys2-Cys17, Cys9-Cys22, Cys16-Cys29)
Sequence Shortening

GCKGFGDSCTPGKNECCPNYACSSKHKWCKVYL-NH2 (Disulfide bonds: Cys2-Cys17, Cys9-Cys22, Cys16-Cys29)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Hainantoxin-III 相关分类

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  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Hainantoxin-III1809149-40-3Sodium ChannelNa channelsNa+ channelsPotassium ChannelInhibitorinhibitorinhibit

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