2. Immunology/Inflammation
  3. NO Synthase
  4. Kansuinine E

Kansuinine E 是一种植物源性 nitric oxide 抑制剂 (IC50=6.3 μM)。Kansuinine E 属于麻风类二萜，从 E. kansui 根中分离得到。

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Kansuinine E Chemical Structure

Kansuinine E Chemical Structure

CAS No. : 672945-84-5

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Kansuinine E 相关抗体

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nNOS iNOS eNOS

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Kansuinine E is a plant-derived nitric oxide inhibitor (IC50=6.3 μM). Kansuinine E belongs to jatrophane-type diterpenoids and is isolated from the roots of E. kansui[1].

IC50 & Target

IC50: 6.3 μM (nitric oxide)[1].
细胞效力
(Cellular Effect)
Cell Line Type Value Description References
NIH3T3 ED50
> 50 μg/mL
Compound: 5, kansuinin E
Survival effect on NGF-dependent mouse NIH/3T3 cells expressing TrkB assessed as cell viability after 2 days by MTT assay
Survival effect on NGF-dependent mouse NIH/3T3 cells expressing TrkB assessed as cell viability after 2 days by MTT assay
[PMID: 15387657]
NIH3T3 ED50
0.23 μg/mL
Compound: 5, kansuinin E
Survival effect on NGF-dependent mouse NIH/3T3 cells expressing TrkA assessed as cell viability after 2 days by MTT assay
Survival effect on NGF-dependent mouse NIH/3T3 cells expressing TrkA assessed as cell viability after 2 days by MTT assay
[PMID: 15387657]
分子量

777.81

Formula

C41H47NO14
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Kansuinine E 相关分类

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The molarity calculator equation

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质量   浓度   体积   分子量 *
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Kansuinine E672945-84-5NO SynthaseNitric oxide synthasesNOSplant-derivedjatrophane-typediterpenoidsrootsE. kansuiInhibitorinhibitorinhibit

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