2. GPCR/G Protein
  3. Angiotensin Receptor
  4. L-162313

L-162313 是一种非肽血管紧张素 II AT1 和 AT2 受体激动剂，对于 AT1 和 AT2 受体的 IC50 值分别为 1.1 和 2.0 nM。L-162313 可用于血管收缩、醛固酮释放和心血管生长的研究。

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L-162313 Chemical Structure

L-162313 Chemical Structure

CAS No. : 151488-11-8

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规格 价格 是否有货 数量
1 mg ￥3990
1 - 2 周
5 mg 现货 1 - 2 周
10 mg 现货 1 - 2 周
50 mg   询价  
100 mg   询价  

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L-162313 相关抗体

Top Publications Citing Use of Products

查看 Angiotensin Receptor 亚型特异性产品:

查看所有亚型
AT1 Receptor AT2 Receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

L-162313 is a non-peptide angiotensin II AT1 and AT2 receptor agonist, with IC50 values of 1.1 and 2.0 nM for AT1 and AT2 receptor, respectively. L-162313 can be used for the research of vasoconstriction, aldosterone release, and cardiovascular growth[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
COS-7 IC50
1.1 nM
Compound: L-162313
Displacement of [125I]angiotensin 2 from rat AT1 receptor expressed in african green monkey COS7 cells after 24 hrs
Displacement of [125I]angiotensin 2 from rat AT1 receptor expressed in african green monkey COS7 cells after 24 hrs
[PMID: 20493713]
COS-7 IC50
2 nM
Compound: L-162313
Displacement of [125I]angiotensin 2 from rat AT2 receptor expressed in african green monkey COS7 cells after 24 hrs
Displacement of [125I]angiotensin 2 from rat AT2 receptor expressed in african green monkey COS7 cells after 24 hrs
[PMID: 20493713]
分子量

582.78

Formula

C30H38N4O4S2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

L-162313 相关分类

  • 摩尔计算器

  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

L-162313151488-11-8L162313L 162313Angiotensin Receptornon-peptidevasoconstrictionaldosterone releasecardiovascular growthInhibitorinhibitorinhibit

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产品名称：
L-162313
目录号：
HY-112824
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