2. Immunology/Inflammation Metabolic Enzyme/Protease
  3. COX Lipoxygenase
  4. L-651896

L-651896 是一种具有抗炎和抗增殖活性的化合物，通过抑制 5-脂氧合酶 (5-lipoxygenase) 和环氧合酶 (cyclooxygenase)，来减少白三烯和前列腺素的生成。L-651896 可用于皮肤疾病和其他炎症性疾病中研究。

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L-651896 Chemical Structure

L-651896 Chemical Structure

CAS No. : 99134-29-9

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L-651896 相关抗体

Top Publications Citing Use of Products

查看 COX 亚型特异性产品:

查看所有亚型
COX COX-1 COX-2 COX-3

查看 Lipoxygenase 亚型特异性产品:

查看所有亚型
5-LOX 12-LOX 15-LOX

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

L-651896 is a compound with anti-inflammatory and antiproliferative activities that inhibits 5-lipoxygenase and cyclooxygenase, thereby reducing the production of leukotrienes and prostaglandins. L-651896 can be used in the study of skin diseases and other inflammatory diseases[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
RBL-1 IC50
0.25 μM
Compound: L-651896
Ability to inhibit 5-lipoxygenase by using a crude preparation of the cytosolic enzyme from the rat basophilic leukemia (RBL-1) cell line
Ability to inhibit 5-lipoxygenase by using a crude preparation of the cytosolic enzyme from the rat basophilic leukemia (RBL-1) cell line
[PMID: 2104936]
分子量

282.33

Formula

C18H18O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

L-651896 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

L-65189699134-29-9L651896L 651896COXLipoxygenaseCyclooxygenaseLOXAnti-inflammatory activityantiproliferative activityprostaglandinsleukotriene5-lipoxygenaseInhibitorinhibitorinhibit

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目录号：
HY-19023
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