2. Metabolic Enzyme/Protease
  3. DAGL MAGL
  4. LEI-106

LEI-106 是一种有效的双重 DAGL-α/ABHD6 抑制剂，对 DAGL-α 的 IC50 为 18 nM，对 ABHD6 的 Ki 为 0.8 μM。LEI-106 抑制 DAGL-α 的天然底物 [14C]-sn-1-oleoyl-2-arachidonoyl-glycerol 的水解，Ki 为 0.7 μM。

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LEI-106 Chemical Structure

LEI-106 Chemical Structure

CAS No. : 1620582-23-1

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规格 价格 是否有货 数量
1 mg ￥950
3 - 4 周
5 mg   询价  
10 mg   询价  

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LEI-106 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

LEI-106 is a potent, dual sn-1-Diacylglycerol lipase α (DAGL-α)/ABHD6 inhibitor with an IC50 of 18 nM for DAGL-α and a Ki of 0.8 μM for ABHD6. LEI-106 inhibits the hydrolysis of [14C]-sn-1-oleoyl-2-arachidonoyl-glycerol, the natural substrate of DAGL-α, with a Ki of 0.7 μM[1].

分子量

481.56

Formula

C26H27NO6S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

LEI-106 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LEI-1061620582-23-1LEI106LEI 106DAGLMAGLDiacylglycerol lipaseDAG lipaseDGLMonoacylglycerol lipasesn-1-Diacylglycerol lipase αDAGL-αα/β-hydrolase domain 6ABHD6diet-induced obesitymetabolic syndromeInhibitorinhibitorinhibit

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目录号：
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