2. Vitamin D Related/Nuclear Receptor Metabolic Enzyme/Protease Immunology/Inflammation
  3. Glycosidase Dipeptidyl Peptidase Estrogen Receptor/ERR Aryl Hydrocarbon Receptor
  4. Lupinalbin A

Lupinalbin A  (Synonyms: Boeravinone L)

目录号: HY-N4069
产品使用指南 技术支持

Lupinalbin A (Boeravinone L) 是一种二肽基肽酶 4 (DPP4) 和 α-葡萄糖苷酶 (α‑glucosidase) 抑制剂，IC50 值分别为 45.2 和 53.4 µM。Lupinalbin A 具有抗糖尿病活性。

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Lupinalbin A Chemical Structure

Lupinalbin A Chemical Structure

CAS No. : 98094-87-2

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Lupinalbin A 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Lupinalbin A (Boeravinone L) is a dipeptidyl peptidase 4 (DPP4) and α-glucosidase inhibitor with IC50 values ​​of 45.2 and 53.4 µM, respectively. Lupinalbin A exhibits antidiabetic activity[1].

IC50 & Target[1]

DPP-4

45.2 μM (IC50)

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
RAW264.7 IC50
> 1 μM
Compound: 2
Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells pretreated for 1 hr followed by LPS-stimulation and measured after 24 hrs by Griess assay
Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells pretreated for 1 hr followed by LPS-stimulation and measured after 24 hrs by Griess assay
[PMID: 29932657]
分子量

284.22

Formula

C15H8O6
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Lupinalbin A 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Lupinalbin A98094-87-2Boeravinone LGlycosidaseDipeptidyl PeptidaseEstrogen Receptor/ERRAryl Hydrocarbon ReceptorDPPAhRInhibitorinhibitorinhibit

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