2. GPCR/G Protein Neuronal Signaling
  3. Adrenergic Receptor
  4. Mabuterol hydrochloride

Mabuterol hydrochloride 是一种选择性和具有口服活性的 β-2 肾上腺素能受体 (ADRB2) 激动剂。Mabuterol hydrochloride 抑制抑制 PDGF-BB 诱导的细胞增殖和细胞内 Ca2+ 增加。Mabuterol hydrochloride 抑制 PDGF-BB 诱导的 Drp-1、cyclinD1 和 PCNA 蛋白表达，并增强 Mfn-2 表达。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Mabuterol hydrochloride Chemical Structure

Mabuterol hydrochloride Chemical Structure

CAS No. : 54240-36-7

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Mabuterol hydrochloride 的其他形式现货产品:

Customer Review

Other Forms of Mabuterol hydrochloride:

Mabuterol hydrochloride 相关抗体

Top Publications Citing Use of Products

查看 Adrenergic Receptor 亚型特异性产品:

查看所有亚型
α adrenergic receptor β adrenergic receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Mabuterol hydrochloride is a selective and orally active beta-2 adrenergic receptor (ADRB2) agonist. Mabuterol hydrochloride inhibits the proliferation and suppresses the increase of intracellular Ca2+ induced by PDGF-BB. Mabuterol hydrochloride suppresses the protein expressions of Drp-1, cyclinD1 and PCNA and enhanced the expression of Mfn-2 induced by PDGF-BB[1][2].

IC50 & Target[1]

Beta-2 adrenergic receptor

 

体外研究
(In Vitro)

Mabuterol hydrochloride (10-60 µM; 48 h) 抑制 PDGF-BB 诱导的 ASMC 增殖[2]。
Mabuterol hydrochloride (50 µM; 1h) 抑制 PDGF-BB (25ng/ml) 诱导的细胞内 Ca2+ 增加[2]。
Mabuterol hydrochloride(50 µM; 48 h) 显着抑制 PDGF-BB 诱导的 Drp-1、cyclinD1 和 PCNA 蛋白表达，并增强 Mfn-2 表达[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Mabuterol hydrochloride 相关抗体:

Cell Viability Assay[2]

Cell Line: rat ASMCs
Concentration: 10, 20, 30, 40, 50, 60 µM
Incubation Time: 24, 48 h
Result: Inhibited the proliferation of ASMCs induced by PDGF-BB (25 ng/ml) in a dose-dependent maner at 48 h.
分子量

347.20

Formula

C13H19Cl2F3N2O
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Mabuterol hydrochloride 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Mabuterol54240-36-7Adrenergic ReceptorBeta ReceptorASMCsDrp-1cyclinD1PCNAPDGF-BBMfn-2Ca2+Inhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
Mabuterol hydrochloride
目录号：
HY-W755295
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z