2. Immunology/Inflammation NF-κB Metabolic Enzyme/Protease
  3. Reactive Oxygen Species NOD-like Receptor (NLR)
  4. Macarangin

Macarangin 可以从蜂胶中分离得到。 Macarangin 具有清除 DPPH 自由基的活性，并通过抑制 NLRP3 炎症小体的激活过程显示出抗炎活性。

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Macarangin Chemical Structure

Macarangin Chemical Structure

CAS No. : 129385-65-5

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规格 价格 是否有货 数量
1 mg ￥8288
1 - 2 周
5 mg   询价  
10 mg   询价  

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Macarangin 相关抗体

Top Publications Citing Use of Products

查看 NOD-like Receptor (NLR) 亚型特异性产品:

查看所有亚型
NLRP3 NLRP1 NOD1 NOD2

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Macarangin can be isolated from propolis. Macarangin has DPPH radical-scavenging activity and shows anti-inflammatory activities via inhibiting the activation process of NLRP3 inflammasome[1][2].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A549 IC50
> 0.0001 x 10-5 M
Compound: 23
Cytotoxicity against human A549 cells after 72 hrs by XTT assay
Cytotoxicity against human A549 cells after 72 hrs by XTT assay
[PMID: 20619940]
HeLa IC50
> 0.0001 x 10-5 M
Compound: 23
Cytotoxicity against human HeLa cells after 72 hrs by XTT assay
Cytotoxicity against human HeLa cells after 72 hrs by XTT assay
[PMID: 20619940]
HT-29 IC50
> 0.0001 x 10-5 M
Compound: 23
Cytotoxicity against human HT-29 cells after 72 hrs by XTT assay
Cytotoxicity against human HT-29 cells after 72 hrs by XTT assay
[PMID: 20619940]
NCI-H460 IC50
5.7 μM
Compound: 5
Inhibition of ABCG2 expressed in human NCI-H460 cells assessed as inhibition of PhA accumulation after 2 to 20 hrs relative to fumitremorgin C
Inhibition of ABCG2 expressed in human NCI-H460 cells assessed as inhibition of PhA accumulation after 2 to 20 hrs relative to fumitremorgin C
[PMID: 21275386]
分子量

422.47

Formula

C25H26O6
CAS 号
结构分类
初始来源

Kenyan propolis
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Macarangin 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Macarangin129385-65-5Reactive Oxygen SpeciesNOD-like Receptor (NLR)DPPHanti-inflammatoryInhibitorinhibitorinhibit

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目录号：
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