2. GPCR/G Protein Neuronal Signaling
  3. mGluR
  4. MGS0028

MGS0028 是一种选择性代谢型谷氨酸 2/3 (mGlu2/3) 受体激动剂。MGS0028 可用于精神疾病研究。

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MGS0028 Chemical Structure

MGS0028 Chemical Structure

CAS No. : 321963-33-1

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MGS0028 相关抗体

Top Publications Citing Use of Products

查看 mGluR 亚型特异性产品:

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mGluR1 mGluR2 mGluR3 mGluR4 mGluR5 mGluR6 mGluR7 mGluR8 mGluR

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

MGS0028 is a selective metabotropic glutamate 2/3 (mGlu2/3) receptor agonist. MGS0028 can be used for psychiatric disorders research[1].

IC50 & Target[1]

mGlu2 Receptor

 

mGluR3R

 

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
CHO EC50
0.57 nM
Compound: (+)-14
Agonist activity against Metabotropic glutamate receptor 2 expressed in CHO cells was evaluated by measuring forskolin-induced cyclic AMP formation
Agonist activity against Metabotropic glutamate receptor 2 expressed in CHO cells was evaluated by measuring forskolin-induced cyclic AMP formation
[PMID: 11123999]
CHO EC50
1.26 nM
Compound: (+/-)-14
Agonist activity against Metabotropic glutamate receptor 2 expressed in CHO cells was evaluated by measuring forskolin-induced cyclic AMP formation
Agonist activity against Metabotropic glutamate receptor 2 expressed in CHO cells was evaluated by measuring forskolin-induced cyclic AMP formation
[PMID: 11123999]
CHO EC50
94.7 nM
Compound: (-)-14
Agonist activity against Metabotropic glutamate receptor 2 expressed in CHO cells was evaluated by measuring forskolin-induced cyclic AMP formation
Agonist activity against Metabotropic glutamate receptor 2 expressed in CHO cells was evaluated by measuring forskolin-induced cyclic AMP formation
[PMID: 11123999]
分子量

217.15

Formula

C8H8FNO5
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

MGS0028 相关分类

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MGS0028321963-33-1MGS 0028MGS-0028mGluRMetabotropic glutamate receptorspsychiatric disordersmGlu2/3 receptorInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-131287
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