2. Anti-infection
  3. Antibiotic Bacterial
  4. Micronomicin sulfate

Micronomicin sulfate  (Synonyms: 硫酸小诺霉素; Gentamicin C2b sulfate; Antibiotic XK-62-2 sulfate; Sagamicin sulfate)

目录号: HY-108307 纯度: ≥98.0%
COA 产品使用指南

摩尔计算器

Micronomicin sulfate (Gentamicin C2b sulfate) 是从 Micromonospora 中分离出来的氨基糖苷抗生素 (antibiotic)。Micronomicin sulfate 是一种接近庆大霉素类抗生素的广谱抗生素，对假单胞菌、变形杆菌、肺炎克雷伯菌、沙雷菌等具有高的抑制活性 (MIC=0.001-8.3 μg/ml)。

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Micronomicin sulfate Chemical Structure

Micronomicin sulfate Chemical Structure

CAS No. : 66803-19-8

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规格 价格 是否有货 数量
25 mg ￥344
In-stock
50 mg ￥630
In-stock
100 mg ￥920
In-stock
200 mg   询价  
500 mg   询价  

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Customer Review

Other Forms of Micronomicin sulfate:

Micronomicin sulfate 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Micronomicin sulfate (Gentamicin C2b sulfate) is an aminoglycoside antibiotic isolated from Micromonospora. Micronomicin sulfate is a broad-spectrum antibiotic close to the gentamicin-type antibiotics, exhibits a high activity against Pseudomonas, Proteus, Klebsiella pneumoniae, Serratia, etc (MIC=0.001-8.3 μg/ml)[1][2].

IC50 & Target

Aminoglycoside

 

体外研究
(In Vitro)

Micronomicin has a potent antibacterial activity, it is active against Staphylococcus aureus FDA 209 P, Staphylococcus aureus with the minimal inhibitory values of 0.01 μg/ml. It is also against Escherichia coli St.M. 589, Baker 2, F 14-BK, and R5/W677 with the minimal inhibitory values of 0.75 μg/ml, 0.3 μg/ml, 0.03 μg/ml and 0.03 μg/ml. And it is active against Pseudomonas aeruginosa strains and lebsiella pneumoniae strains (MICs = 0.03-17.5 μg/ml)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Micronomicin sulfate 相关抗体:
体内研究
(In Vivo)

Micronomicin sulfate is highly active against various bacterial infections in mice, and has an intravenous acute LD50 in mice of 93 mg/kg[1].
Micronomicin sulfate (intravenous injection; 4-100 mg/kg; 30 days) is injected for subacute toxicity study. The wistar rats dies at the dose level of 100 mg/kg (10 out of 30 animals): renal disorders and ataxia. The renal histological disorders occurrs mainly at the dose levels of 25 mg/kg and over[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Wistar rats[3]
Dosage: 4, 10, 25, 63 mg/kg and 100 mg/kg
Administration: Intravenous injection; 30 days
Result: Led to death of rat at 100 mg/kg.
Formula

C20H41N5O7.xH2SO4
CAS 号
性状

固体

颜色

White to yellow

中文名称

硫酸小诺霉素；沙加霉素
结构分类
初始来源

Micromonospora
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶解性数据
细胞实验： 

H2O 中的溶解度 : 50 mg/mL (超声助溶)

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物实验：

以下溶解方案，请直接配制工作液。建议现用现配，在短期内尽快用完。 以下溶剂前显示的百分比是指该溶剂在您配制终溶液中的体积占比； 如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶。

  • 方案 一

    请依序添加每种溶剂： PBS

    Solubility: 100 mg/mL; 澄清溶液; 超声助溶

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
该产品水溶性佳，请具体参考实测 水 / PBS / Saline 中的溶解度数据。
您所需的储备液浓度超过该产品的实测溶解度，如有需要，请与 MCE 中国技术支持联系。
纯度 & 产品资料

纯度: ≥98.0%

COA (294 KB) HNMR (195 KB) MS (68 KB)

产品使用指南 (1538 KB)
参考文献

Micronomicin sulfate 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Micronomicin66803-19-8Gentamicin C2bAntibiotic XK-62-2Sagamicin硫酸小诺霉素沙加霉素AntibioticBacterialStaphylococcus aureusBacillus subtilisEscherichia coliBaker 2F 14-BKand R5/W677bacterialinfectionInhibitorinhibitorinhibit

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