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(-)-Amosulalol  (Synonyms: (-)-YM 09538)

目录号: HY-106720B
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摩尔计算器

(-)-Amosulalol ((-)-YM 09538) 是一种α,β-阻滞剂，具有在小鼠体内的药代动力学和代谢相关活性。在小鼠中，(-)-Amosulalol静脉注射后血浆浓度呈双相下降，口服后达到最大血浆浓度的时间为0.25h，之后下降，全身生物利用度为38.7%，主要通过尿液排泄，尿液中可检测到多种代谢产物，在胆汁样本中发现了新的代谢产物amosulalol carbamoyl glucuronide。

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(-)-Amosulalol Chemical Structure

(-)-Amosulalol Chemical Structure

CAS No. : 94666-15-6

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规格 是否有货
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Other Forms of (-)-Amosulalol:

(-)-Amosulalol 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(-)-Amosulalol ((-)-YM 09538) is an α,β-blocker with pharmacokinetic and metabolic activities in mice. In mice, the plasma concentration of (-)-Amosulalol decreased in a biphasic manner after intravenous injection. The time to reach the maximum plasma concentration after oral administration was 0.25h, and then decreased. The systemic bioavailability was 38.7%, and it was mainly excreted through urine. Multiple metabolites were detected in urine, and a new metabolite amosulalol carbamoyl glucuronide was found in bile samples.

分子量

380.46

Formula

C18H24N2O5S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

(-)-Amosulalol 相关分类

  • 摩尔计算器

  • 稀释计算器

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Keywords:

(-)-Amosulalol94666-15-6(-)-YM 09538OthersInhibitorinhibitorinhibit

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