2. GPCR/G Protein
  3. P2Y Receptor
  4. MRS2768 tetrasodium salt

MRS2768 tetrasodium salt 是一种中等效力和选择性的 P2Y2 受体激动剂。MRS2768 tetrasodium salt 对心肌细胞缺血损伤具有保护作用。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

MRS2768 tetrasodium salt Chemical Structure

MRS2768 tetrasodium salt Chemical Structure

CAS No. : 2567869-47-8

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货 数量
1 mg ￥9547
3 - 4 周
5 mg   询价  
10 mg   询价  

* Please select Quantity before adding items.

Customer Review

MRS2768 tetrasodium salt 相关抗体

Top Publications Citing Use of Products

查看 P2Y Receptor 亚型特异性产品:

查看所有亚型
P2Y1 Receptor P2Y2 Receptor P2Y6 Receptor P2Y12 Receptor P2Y13 Receptor P2Y14 Receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

MRS2768 tetrasodium salt is a moderately potent and selective P2Y2 receptor agonist. MRS2768 tetrasodium salt has a protective effect on cardiomyocytes from ischemic damage in vivo and in vitro[1][2].

IC50 & Target

P2Y2 Receptor

 

体外研究
(In Vitro)

MRS2768 (0.01-10000 μM; 24 hours) significantly increases the proliferation of PANC-1 cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

MRS2768 tetrasodium salt 相关抗体:

Cell Proliferation Assay[1]

Cell Line: Human pancreatic duct epithelial cells PANC-1
Concentration: 0.01, 0.1, 1, 10, 100, 1000, 10000 μM
Incubation Time: 24 hours
Result: The effect on proliferation of PANC-1 cells was dependent on concentration (0.1 μM to 1 mM). The concentration that elicited a half-maximal response (EC50) in the stimulation of proliferation was 0.8±1.7 μM.
Resulted in a dose- and time-dependent increase of proliferation in PANC-1 cells
体内研究
(In Vivo)

MRS2768 (4.44 μg/kg i.v.) pretreatment reduces myocardial damage in mice. MRS2768 has a protective effect on cardiomyocytes from ischemic damage in vivo[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male wild-type mice (C57BL)[2]
Dosage: 4.44 μg/kg
Administration: Injected i.v.; 1 h before myocardial infarct (MI)
Result: Pretreatment reduced myocardial damage. The damage was significantly smaller in mice compare to the untreated mice (25.6±4.5% vs. 39.2±6.3%).
分子量

728.14

Formula

C15H16N2Na4O18P4
CAS 号
性状

液体

颜色

Colorless to light yellow

运输条件

Shipping with dry ice.
储存方式

-80°C
纯度 & 产品资料
参考文献

MRS2768 tetrasodium salt 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MRS2768 tetrasodium2567869-47-8P2Y ReceptorP2Y2protectiveeffectcardiomyocytesischemicdamageInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
MRS2768 tetrasodium salt
目录号：
HY-108649A
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z