2. Antibody-drug Conjugate/ADC Related
  3. ADC Cytotoxin
  4. N-Ac-γ-Calicheamicin-AcBut-NHS ester

N-Ac-γ-Calicheamicin-AcBut-NHS ester 

目录号: HY-103688
产品使用指南

摩尔计算器

AcBut-N-Ac-γ-Calicheamicin 是一种 ADC 毒性分子，通过引发 DNA 双链断裂来诱导细胞周期阻滞和凋亡 (Apoptosis)。AcBut-N-Ac-γ-Calicheamicin 主要用于合成抗体药物偶联物 (ADC)，有望用于抗癌领域研究，如急性淋巴细胞白血病 (ALL) 和其他血液系统恶性肿瘤研究。

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N-Ac-γ-Calicheamicin-AcBut-NHS ester Chemical Structure

N-Ac-γ-Calicheamicin-AcBut-NHS ester Chemical Structure

CAS No. : 174885-02-0

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     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

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N-Ac-γ-Calicheamicin-AcBut-NHS ester 相关抗体

Top Publications Citing Use of Products

查看 ADC Cytotoxin 亚型特异性产品:

查看所有亚型
Auristatin Calicheamicins Camptothecins Daunorubicins/Doxorubicins Duocarmycins Maytansinoids Pyrrolobenzodiazepines Traditional Cytotoxic Agents

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

AcBut-N-Ac-γ-Calicheamicin is an ADC cytotoxic payload that induces cell cycle arrest and apoptosis by causing DNA double-strand breaks. AcBut-N-Ac-γ-Calicheamicin is primarily used in the synthesis of antibody-drug conjugates (ADC) and holds promise for research in the field of cancer, including acute lymphoblastic leukemia (ALL) and other hematological malignancies[1].

分子量

1779.73

Formula

C77H99IN6O28S3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

N-Ac-γ-Calicheamicin-AcBut-NHS ester 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

N-Ac-γ-Calicheamicin-AcBut-NHS ester174885-02-0ADC CytotoxinADC PayloadInhibitorinhibitorinhibit

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目录号：
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