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  3. NaPi2b-IN-1

NaPi2b-IN-1 是一种有效的口服活性钠依赖性磷酸转运蛋白 2b (NaPi2b) 抑制剂,IC50 为 64 nM。NaPi2b 主要在小肠、肺和睾丸中表达,在磷酸盐稳态中起重要作用。NaPi2b-IN-1具有研究高磷血症的潜力。

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NaPi2b-IN-1 Chemical Structure

NaPi2b-IN-1 Chemical Structure

CAS No. : 1453116-06-7

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  • 生物活性

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生物活性

NaPi2b-IN-1 is a potent and orally active inhibitor of sodium-dependent phosphate transport protein 2b (NaPi2b) with an IC50 of 64 nM. NaPi2b is primarily expressed in the small intestine, lungs, and testes and plays an important role in phosphate homeostasis. NaPi2b-IN-1 has the potential for the research of hyperphosphatemia[1].

分子量

943.46

Formula

C44H58ClF3N4O11S

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

NaPi2b-IN-1 相关分类

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
NaPi2b-IN-1
目录号:
HY-142957
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