2. GPCR/G Protein Neuronal Signaling
  3. Adrenergic Receptor
  4. Pafenolol

Pafenolol 是一种具有口服活性的选择性 β1 肾上腺素能受体 (β1-adrenergic receptor) 阻断剂，可有效降低血压。在大鼠中的药代动力学研究表明，Pafenolol 的吸收会受到胃肠道内容物的影响，其生物利用度会因为食物摄入而降低。Pafenolol 可用于心血管疾病及哮喘领域的研究。

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Pafenolol Chemical Structure

Pafenolol Chemical Structure

CAS No. : 75949-61-0

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Pafenolol 相关抗体

Top Publications Citing Use of Products

查看 Adrenergic Receptor 亚型特异性产品:

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α adrenergic receptor β adrenergic receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Pafenolol is a selectively oral-active β1 adrenergic receptor (β1-adrenergic receptor) antagonist that effectively lowers blood pressure. Pharmacokinetic studies in rats indicate that the absorption of Pafenolol is influenced by gastrointestinal contents, with food intake reducing the bioavailability of Pafenolol in rats. Pafenolol can be used in research related to cardiovascular diseases and asthma[1].

IC50 & Target

Beta-1 adrenergic receptor

 

分子量

337.46

Formula

C18H31N3O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Pafenolol 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pafenolol75949-61-0Adrenergic ReceptorBeta ReceptorInhibitorinhibitorinhibit

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