2. Cell Cycle/DNA Damage Vitamin D Related/Nuclear Receptor Metabolic Enzyme/Protease
  3. PPAR
  4. PPARγ agonist 15

PPARγ agonist 15 (Compound 7c) 是 PPARγ 的激动剂。PPARγ agonist 15 抑制 α-淀粉酶 (HPA) 和 α-葡萄糖苷酶 (HLAG) 的表达，IC50 分别为 28.35 µM 和 26.21 µM。PPARγ agonist 15 在 L6 肌管细胞中增加葡萄糖摄取。PPARγ agonist 15 在大鼠 Streptozotocin (HY-13753)-诱发的糖尿病模型中改善葡萄糖稳态、胰岛素敏感性和脂质代谢。

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PPARγ agonist 15 Chemical Structure

PPARγ agonist 15 Chemical Structure

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PPARγ agonist 15 相关抗体

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PPARα PPARβ/δ PPARγ PPAR PPARδ

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

PPARγ agonist 15 (Compound 7c) is an agonist for PPARγ. PPARγ agonist 15 inhibits the expression of alpha-amylase (HPA) and alpha-glucosidase (HLAG) with IC50 of 28.35 µM and 26.21 µM. PPARγ agonist 15 enhances glucose uptake in the L6 myotube cell. PPARγ agonist 15 improves glucose homeostasis, insulin sensitivity, and lipid metabolism in rat Streptozotocin (HY-13753)-induced diabetes model[1].

分子量

436.51

Formula

C21H16N4O3S2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

PPARγ agonist 15 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PPARγ agonist 15PPARγ agonist15PPARγ agonist-15PPARPeroxisome proliferator-activated receptorsWistar ratdiabetesInhibitorinhibitorinhibit

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产品名称：
PPARγ agonist 15
目录号：
HY-169404
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