2. Immunology/Inflammation
  3. PGE synthase
  4. Prostaglandin E2 Inhibitor 3

Prostaglandin E2 Inhibitor 3 (Compound 3) 是一种选择性微粒体前列腺素 E 合酶-1 (mPGES-1) 抑制剂 (IC50 = 0.2 µM)。Prostaglandin E2 Inhibitor 3 对 mPGES-1 的选择性高于环氧合酶 (COX)-1/2、5-脂氧合酶 (5-LO) 和可溶性环氧化物水解酶 (sEH)。Prostaglandin E2 Inhibitor 3 具有抗炎活性，可减弱酵母聚糖诱导的小鼠腹膜白细胞迁移。

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Prostaglandin E2 Inhibitor 3 Chemical Structure

Prostaglandin E2 Inhibitor 3 Chemical Structure

CAS No. : 3054217-03-4

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Prostaglandin E2 Inhibitor 3 相关抗体

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生物活性

Prostaglandin E2 Inhibitor 3 (Compound 3) is a selectivity microsomal prostaglandin E synthase-1 (mPGES-1) inhibitor (IC50 = 0.2 µM). Prostaglandin E2 Inhibitor 3 has higher selectivity for mPGES-1 than cyclooxygenases (COX)-1/2, 5-lipoxygenase (5-LO), and soluble epoxide hydrolase (sEH). Prostaglandin E2 Inhibitor 3 has anti-inflammatory activity and can attenuate zymosan-induced peritoneal leukocyte migration in mice[1].

分子量

452.32

Formula

C21H14BrN3O2S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Prostaglandin E2 Inhibitor 3 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Prostaglandin E2 Inhibitor 33054217-03-4PGE synthaseProstaglandin E synthasemPGES-1COX-1/25-lipoxygenase5-LOsEHanti-inflammatoryInhibitorinhibitorinhibit

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