2. PROTAC Anti-infection
  3. PROTACs HIV
  4. PROTAC Vif degrader-1

PROTAC Vif degrader-1 (Compound L15) 是一种 Vif PROTAC 降解剂。PROTAC Vif degrader-1 具有抗 HIV-1 病毒活性 (抗 HIV-1IIIB 的 EC50: 33.35 μM )。蓝色: CRBN 配体 (HY-10984)；黑色: 连接子；粉色: HIV-1 抑制剂 (HY-163852)。

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PROTAC Vif degrader-1 Chemical Structure

PROTAC Vif degrader-1 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
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Customer Review

PROTAC Vif degrader-1 相关抗体

Top Publications Citing Use of Products

查看 PROTACs 亚型特异性产品:

查看所有亚型
von Hippel-Lindau (VHL) Cereblon MDM2 cIAP1

查看 HIV 亚型特异性产品:

查看所有亚型
HIV HIV-1 HIV-2

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

PROTAC Vif degrader-1 (Compound L15) is a Vif PROTAC degrader. PROTAC Vif degrader-1 has antiviral activity against HIV-1 (EC50: 33.35 μM against HIV-1IIIB). Blue: CRBN ligand (HY-10984); Black: linker; Pink: HIV-1 inhibitor(HY-163852)[1].

IC50 & Target[1]

HIV (IIIB)

33.35 μM (EC50)

体外研究
(In Vitro)

PROTAC Vif degrader-1 可抑制 PBMCs 中不同野生型 HIV-1 菌株的复制 （对于 HIV-1kiz002 和 HIV-1WAN EC50 分别为 10.53 μM 和 8.76 μM)，且细胞毒性较低 (CC50: > 200 µM)[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

PROTAC Vif degrader-1 相关抗体:
分子量

855.87

Formula

C41H41N7O12S
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

PROTAC Vif degrader-1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PROTAC Vif degrader-1PROTAC Vif degrader1PROTAC Vif degrader 1PROTACsHIVHuman immunodeficiency virusVif degraderantiviralInhibitorinhibitorinhibit

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产品名称：
PROTAC Vif degrader-1
目录号：
HY-163851
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