2. Anti-infection Immunology/Inflammation
  3. Antibiotic Bacterial NO Synthase
  4. Rabelomycin

Rabelomycin 是一种抗生素，对革兰氏阳性菌具有抗菌活性。Rabelomycin 对诱导型一氧化氮合酶 (iNOS) 具有抑制活性，IC50 为 63.9 μM。

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Rabelomycin Chemical Structure

Rabelomycin Chemical Structure

CAS No. : 28399-50-0

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Rabelomycin 相关抗体

Top Publications Citing Use of Products

查看 Antibiotic 亚型特异性产品:

查看所有亚型
Aminoglycoside Glycopeptide Lipopeptide Macrolide Oxazolidinone Quinolone Tetracycline β-lactam

查看 NO Synthase 亚型特异性产品:

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nNOS iNOS eNOS

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Rabelomycin is antibiotic, which exhibits antimicrobial activity against gram positive bacteria. Rabelomycin exhibits inhibitory activity against inducible nitric oxide synthase (iNOS) with an IC50 of 63.9 μM[1][2].

IC50 & Target

iNOS

63.9 μM (IC50)

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
MCF7 IC50
4.28 μM
Compound: 8
Cytotoxicity against human MCF7 cells by SRB assay
Cytotoxicity against human MCF7 cells by SRB assay
[PMID: 23136829]
NCI-H460 IC50
9.91 μM
Compound: 8
Cytotoxicity against human NCI-H460 cells by SRB assay
Cytotoxicity against human NCI-H460 cells by SRB assay
[PMID: 23136829]
SF-268 IC50
5.54 μM
Compound: 8
Cytotoxicity against human SF268 cells by SRB assay
Cytotoxicity against human SF268 cells by SRB assay
[PMID: 23136829]
分子量

338.31

Formula

C19H14O6
CAS 号
结构分类
初始来源

Streptomyces sp.
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Rabelomycin 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Rabelomycin28399-50-0AntibioticBacterialNO SynthaseNitric oxide synthasesNOSStreptomyces spRAW264.7focal ischemiaAlzheimer's DiseaseHuntington's diseaseInhibitorinhibitorinhibit

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