DCD 蛋白, Human (P.pastoris, His)

N-6*His;Accession#P81605-1 DCD (Y20-L110)

DCD 蛋白存在于汗液中，在细菌定植的早期阶段表现出抗菌活性。分泌的肽形成能够与病原体膜结合并插入其中的同源六聚体复合物。DCD 蛋白插入细菌膜后会产生阴离子通道，可能会改变对细菌生存至关重要的跨膜电位。它对多种病原体表现出高效能，包括大肠杆菌、粪肠球菌、金黄色葡萄球菌和白色念珠菌。DCD 蛋白在类似于汗液的条件下发挥最佳作用，还表现出蛋白水解活性，优先在 Arg 的 C 端侧裂解，在较小程度上裂解 Lys 残基。此外，DCD 蛋白可促进神经元存活并表现出磷酸酶活性，表明其在宿主防御机制中具有多方面的作用。此外，它可能具有与 IgG 结合的能力。

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

Human

P. pastoris

N-6*His

P81605-1 (Y20-L110)

117159  [NCBI]

YDPEAASAPGSGNPCHEASAAQKENAGEDPGLARQAPKPRKQRSSLLEKGLDGAKKAVGGLGKLGKDAVEDLESVGKGAVHDVKDVLDSVL

Approximately 17 kDa. The reducing (R) protein migrat es as 17 kDa in SDS-PAGE may be due to relative charge.

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm sterile filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.