2. 重组蛋白
  3. Cytokines and Growth Factors
  4. EGF Superfamily
  5. EGF
  6. EGF 蛋白, Mouse (HEK293, Fc)

EGF 蛋白, Mouse (HEK293, Fc)

目录号: HY-P72985
产品使用指南

EGF 蛋白是一种生长因子，对于细胞生长、增殖和分化至关重要。它与 EGF 受体结合，激活调节细胞存活和组织修复的信号通路。EGF 蛋白在促进伤口愈合、组织再生和癌症治疗方面具有治疗潜力。它在细胞过程中的作用使其成为生物医学研究的兴趣主题。EGF 蛋白, Mouse (HEK293, Fc) 是重组的 EGF 蛋白，由 HEK293 表达，带有 N-hFc 标签。EGF 蛋白, Mouse (HEK293, Fc) 全长 53 个氨基酸，分子量分别约为 ~44 & 38 kDa。

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SPR 检测服务   重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 μg   询价  
100 μg   询价  

* Please select Quantity before adding items.

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描述

EGF Protein, a growth factor, is essential for cell growth, proliferation, and differentiation. It binds to the EGF receptor, activating signaling pathways that regulate cell survival and tissue repair. EGF Protein has therapeutic potential in promoting wound healing, tissue regeneration, and cancer treatment. Its role in cellular processes makes it a subject of interest in biomedical research. EGF Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived EGF protein, expressed by HEK293 , with N-hFc labeled tag. The total length of EGF Protein, Mouse (HEK293, Fc) is 53 a.a., with molecular weight of ~44 & 38 kDa, respectively.
研究背景

EGF是一种有效的生长因子，可促进体内和体外各种表皮和上皮组织以及细胞培养物中某些成纤维细胞的增殖。它通过激活 EGFR 和镁通道 TRPM6 来刺激肾远曲小管中镁的重吸收，从而起到促镁激素的作用。EGF 还与 EGFR 相互作用，促进 EGFR 二聚化，并与 RHBDF1 和 RHBDF2 形成相互作用，可能调节其细胞内定位和降解。
种属

Mouse
表达系统

HEK293
标签

N-hFc
蛋白编号

P01132 (N977-R1029)
基因 ID
蛋白结构
N-term
hFc
EGF (N977-R1029)
Accession # P01132
C-term
同用名
Pro-epidermal growth factor; Urogastrone; EGF; HOMG4
氨基酸序列

NSYPGCPSSYDGYCLNGGVCMHIESLDSYTCNCVIGYSGDRCQTRDLRWWELR

分子量

Approximately 44&38 kDa
纯度

Greater than 95% as determined by reducing SDS-PAGE
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

EGF Protein, Mouse (HEK293, Fc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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