IL-17D 蛋白, Human

IL-17D protein acts as a potent inducer, effectively triggering endothelial cells to express key inflammatory mediators such as IL6, CXCL8/IL8, and CSF2/GM-CSF. The ability of this cytokine to stimulate the production of pro-inflammatory signals emphasizes its importance in orchestrating immune responses, particularly in the context of endothelial cell activation. IL-17D Protein, Human is the recombinant human-derived IL-17D protein, expressed by E. coli , with tag free. The total length of IL-17D Protein, Human is 185 a.a., with molecular weight of ~20.0 kDa.

IL-17D 蛋白可作为有效的诱导剂，有效触发内皮细胞表达关键炎症介质，例如 IL6、CXCL8/IL8 和 CSF2/GM-CSF。这种细胞因子刺激促炎信号产生的能力强调了其在协调免疫反应中的重要性，特别是在内皮细胞激活的背景下。白细胞介素和趋化因子的诱导表达表明，IL-17D 在塑造炎症环境以及调节内皮细胞介导的免疫和炎症过程中发挥着至关重要的作用。

Human

E. coli

Tag Free

Q8TAD2 (A18-P202)

53342  [NCBI]

APRAGRRPARPRGCADRPEELLEQLYGRLAAGVLSAFHHTLQLGPREQARNASCPAGGRPADRRFRPPTNLRSVSPWAYRISYDPARYPRYLPEAYCLCRGCLTGLFGEEDVRFRSAPVYMPTVVLRRTPACAGGRSVYTEAYVTIPVGCTCVPEPEKDADSINSSIDKQGAKLLLGPNDAPAGP

Approximately 20.0 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of 20 mM Glycine-HCl, 4% Sucrose, 4% Mannitol, 0.02% Tween 80, pH 3.0.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.