2. 重组蛋白
  3. Enzymes & Regulators
  4. Hydrolases (EC 3)
  5. INPP1 蛋白, Human (HEK293, His)

INPP1 蛋白, Human (HEK293, His)

目录号: HY-P70361
产品使用指南

INPP1蛋白，也称为肌醇多磷酸-1-磷酸酶，是一种在肌醇磷酸代谢中起着至关重要作用的磷酸酶。该蛋白质的活性取决于镁离子，负责催化肌醇1,4-二磷酸和肌醇1,3,4-三磷酸1位磷酸基团的水解。INPP1 蛋白, Human (HEK293, His) 是重组的 INPP1 蛋白，由 HEK293 表达，带有 C-6*His 标签。INPP1 蛋白, Human (HEK293, His) 全长 399 个氨基酸，分子量为 40-50 kDa。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

SPR 检测服务   重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 μg   询价  
100 μg   询价  

* Please select Quantity before adding items.

Top Publications Citing Use of Products

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

INPP1 protein, also known as inositol polyphosphate-1-phosphatase, is a phosphatase that plays a crucial role in inositol phosphate metabolism. The activity of this protein depends on magnesium ions and is responsible for catalyzing the hydrolysis of the phosphate group at position 1 of inositol 1,4-bisphosphate and inositol 1,3,4-trisphosphate. INPP1 Protein, Human (HEK293, His) is the recombinant human-derived INPP1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of INPP1 Protein, Human (HEK293, His) is 399 a.a., with molecular weight of 40-50 kDa.
研究背景

INPP1蛋白也称为肌醇多磷酸-1-磷酸酶，是一种磷酸酶，在肌醇磷酸代谢中发挥着至关重要的作用。该蛋白质的活性依赖于镁离子，负责催化肌醇 1,4-二磷酸和肌醇 1,3,4-三磷酸 1 位磷酸基团的水解。这种酶活性对于调节细胞内这些磷酸肌醇分子的水平至关重要。通过去除磷酸基团，INPP1蛋白有助于维持磷酸肌醇信号通路的平衡，该信号通路参与细胞内信号传导、膜运输和囊泡融合等多种细胞过程。INPP1 蛋白在这些过程中的确切作用及其对细胞功能的影响值得进一步研究。
种属

Human
表达系统

HEK293
标签

C-6*His
蛋白编号

P49441 (M1-T399)
基因 ID
蛋白结构
N-term
INPP1 (M1-T399)
Accession # P49441
6*His
C-term
同用名
rHuInositol polyphosphate 1-phosphatase/INPP1, His; Inositol Polyphosphate 1-Phosphatase; IPP; IPPase; INPP1
氨基酸序列

MSDILRELLCVSEKAANIARACRQQEALFQLLIEEKKEGEKNKKFAVDFKTLADVLVQEVIKQNMENKFPGLEKNIFGEESNEFTNDWGEKITLRLCSTEEETAELLSKVLNGNKVASEALARVVHQDVAFTDPTLDSTEINVPQDILGIWVDPIDSTYQYIKGSADIKSNQGIFPCGLQCVTILIGVYDIQTGVPLMGVINQPFVSRDPNTLRWKGQCYWGLSYMGTNMHSLQLTISRRNGSETHTGNTGSEAAFSPSFSAVISTSEKETIKAALSRVCGDRIFGAAGAGYKSLCVVQGLVDIYIFSEDTTFKWDSCAAHAILRAMGGGIVDLKECLERNPETGLDLPQLVYHVENEGAAGVDRWANKGGLIAYRSRKRLETFLSLLVQNLAPAETHT

分子量

40-50 kDa
纯度

Greater than 95% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

INPP1 Protein, Human (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
INPP1 Protein, Human (HEK293, His)
目录号：
HY-P70361
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z