TSLP 蛋白, Human (HEK293, His)

TSLP Protein, a cytokine, stimulates T-cell-attracting chemokine release from monocytes and enhances CD11c(+) dendritic cell maturation. It directly activates mast cells, possibly inducing allergic inflammation. TSLP may also possess antimicrobial properties in the oral cavity and on the skin. TSLP Protein, Human (HEK293, His) is the recombinant human-derived TSLP protein, expressed by HEK293 , with C-10*His labeled tag.

TSLP 蛋白是一种细胞因子，可刺激单核细胞释放 T 细胞吸引趋化因子，对促进 CD11c(+) 树突状细胞的成熟具有特殊作用。此外，这种蛋白质可以直接激活肥大细胞，可能导致过敏性炎症的诱发。还表明 TSLP 在口腔和皮肤上可能具有抗菌特性。

1. Immobilized Anti-Human TSLP mAb at 2 μg/mL (100 μl/well) can bind Human TSLP-His. The ED₅₀ of Recombinant Human TSLP-His is ≤5.6 ng/mL. 
2. Measured by its binding ability in a functional ELISA. Immobilized Human TSLP at 5 μg/ml (100μl/well) on the plate can bind Human TSLPR. The ED₅₀ for this effect is 23.29 ng/mL.

Human

HEK293

C-10*His

Q969D9-1 (Y29-Q159)

85480  [NCBI]

YDFTNCDFEKIKAAYLSTISKDLITYMSGTKSTEFNNTVSCSNRPHCLTEIQSLTFNPTAGCASLAKEMFAMKTKAALAIWCPGYSETQINATQAMKKRRKRKVTTNKCLEQVSQLQGLWRRFNRPLLKQQ

8-10&16-27 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 or PBS, pH 7.4, 8% trehalose.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.