2. GPCR/G Protein Neuronal Signaling MAPK/ERK Pathway Stem Cell/Wnt
  3. Adrenergic Receptor ERK
  4. Salbutamol adipate

Salbutamol adipate  (Synonyms: 沙丁胺醇己二酸盐; Albuterol adipate; AH-3365 adipate)

目录号: HY-B1037B
产品使用指南

摩尔计算器

Salbutamol (Albuterol) adipate 是一种具有口服活性的短效的 β2 肾上腺素受体激动剂。Salbutamol adipate 通过 β2-AR/ERK/EMT 通路促进胃癌细胞的肿瘤发生。Salbutamol adipate 用于研究哮喘和慢性阻塞性肺疾病 (COPD) 引发的支气管痉挛。

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Salbutamol adipate Chemical Structure

Salbutamol adipate Chemical Structure

CAS No. : 149234-08-2

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Salbutamol adipate 的其他形式现货产品:

Other Forms of Salbutamol adipate:

Salbutamol adipate 相关抗体

Top Publications Citing Use of Products

查看 Adrenergic Receptor 亚型特异性产品:

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α adrenergic receptor β adrenergic receptor

查看 ERK 亚型特异性产品:

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ERK ERK1 ERK2 ERK5 ERK8

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Salbutamol (Albuterol) adipate is a short-acting beta-2 adrenergic receptor agonist with oral activity. Salbutamol adipate promotes tumorigenesis of gastric cancer cells through the β2-AR/ERK/EMT pathway. Salbutamol adipate is used to study bronchospasms caused by asthma and chronic obstructive pulmonary disease (COPD)[1][2].

IC50 & Target[1]

β adrenergic receptor

 

体外研究
(In Vitro)

Salbutamol (16 μM, 24 h) adipate 在胃癌细胞中通过 ERK (细胞外信号调节激酶) 磷酸化显著诱导 EMT、迁移和侵袭[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Salbutamol adipate 相关抗体:
体内研究
(In Vivo)

Salbutamol (5 mg/kg/day, 口服, 连续 2 周) adipate 可增加胃癌裸鼠的肿瘤生长能力[1]。
Salbutamol (6 mg/kg, 口服, 连续 4 周) adipate 对 STZ (HY-13753) 诱导的糖尿病大鼠骨骼肌萎缩具有显著的保护作用[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

312.38

Formula

C13H21NO3.1/2C6H10O4
CAS 号
中文名称

沙丁胺醇己二酸盐；柳丁氨醇己二酸盐
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Salbutamol adipate 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Salbutamol149234-08-2AlbuterolAH-3365沙丁胺醇己二酸盐柳丁氨醇己二酸盐AH3365AH 3365Adrenergic ReceptorERKBeta ReceptorExtracellular signal regulated kinasesβ2-ARAgonistMGC803SGC7901COPDInhibitorinhibitorinhibit

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