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  3. Sapitinib fumarate

Sapitinib fumarate  (Synonyms: AZD-8931 fumarate)

目录号: HY-13050A
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Sapitinib fumarate 是可逆的,ATP竞争型 EGFR 抑制剂,对EGFR,ErbB2 和 ErbB3的 IC50 值分别为4,3 和 4 nM。

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Sapitinib fumarate Chemical Structure

Sapitinib fumarate Chemical Structure

CAS No. : 1196531-39-1

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Sapitinib fumarate 的其他形式现货产品:

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Other Forms of Sapitinib fumarate:

    Sapitinib fumarate purchased from MCE. Usage Cited in: Mol Cancer Res. 2019 Jan;17(1):20-29.  [Abstract]

    Western blotting showed that AZD8931 blocks LPEC-1 CM-induced HER3 and AKT phosphorylation. β-actin is used as the loading control.
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    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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