2. 一站式药筛
  3. 化合物库
  4. 类药多样库 Plus
类药多样库 Plus - Lead-like Diverse Library Plus

Cat. No.: HY-L901P

在药物研发过程中，选择具有良好类药性和结构多样性的化合物，是实现化合物对不同疾病靶标具有广泛效果的关键。MCE Lead-like Diverse Library Plus是对50K类药多样库（HY-L901）的进一步补充，该库由 80,000 种类药化合物组成，新增 30,000+ 结构更新颖的类药分子，这些化合物占据更广泛的“化学空间”，是新药发现的有力工具。
  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
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  • 描述&特点
  • 产品资料

描述&特点

Biological Activity

•   Compounds in this library with a high divesity and broad chemical space coverage.

•   Compatible with “Lipinski’s Rule of Five”, with multiple characteristics such as calculated good permeability (-3.2 < logP < 5), oral bioavailability (RotB <= 10), drug transportability (PSA < 120), MW between 300 to 500, number of Hydrogen Bond Donor (HBD) ≤ 5, number of Hydrogen Bond Acceptor (HBA) ≤ 10.

•   Passed all associated MedChem filters, particularly pan assay interference compound (PAINS) motifs, to remove any inappropriate chemical structures and avoid false hits.

•   All compounds are available off the shelf. Pre-plates of 10 mM DMSO solutions, convenient to use.

•   LCMS or NMR validated to ensure high purity and quality.

产品详情

Product Details

•   Compounds in this library with a high divesity and broad chemical space coverage.

•   Compatible with “Lipinski’s Rule of Five”, with multiple characteristics such as calculated good permeability (-3.2 < logP < 5), oral bioavailability (RotB <= 10), drug transportability (PSA < 120), MW between 300 to 500, number of Hydrogen Bond Donor (HBD) ≤ 5, number of Hydrogen Bond Acceptor (HBA) ≤ 10.

•   Passed all associated MedChem filters, particularly pan assay interference compound (PAINS) motifs, to remove any inappropriate chemical structures and avoid false hits.

•   All compounds are available off the shelf. Pre-plates of 10 mM DMSO solutions, convenient to use.

•   LCMS or NMR validated to ensure high purity and quality.

产品资料

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  •  特定化合物
  •  化合物数量
  •  产品排布图
  •  浓度
  •  形式（固体或溶液）
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联系专家定制
  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack

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    产品名称：
    Lead-like Diverse Library Plus
    目录号：
    HY-L901P
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