2. Immunology/Inflammation
  3. SphK
  4. SphK2-IN-1

SphK2-IN-1 是一种 SphK2 抑制剂 (IC50: 0.359 μM)。SphK2-IN-1 可用于癌症，炎症，神经和心血管疾病的研究。

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SphK2-IN-1 Chemical Structure

SphK2-IN-1 Chemical Structure

CAS No. : 2927429-64-7

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SphK2-IN-1 相关抗体

Top Publications Citing Use of Products

查看 SphK 亚型特异性产品:

查看所有亚型
SphK1 SphK2

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

SphK2-IN-1 is a SphK2 inhibitor (IC50: 0.359 μM). SphK2-IN-1 can be used in the research of cancer, inflammation, neurological and cardiovascular disorders[1].

IC50 & Target[1]

SphK2

0.359 μM (IC50)

体外研究
(In Vitro)

SphK2-IN-1 (compound 25b, 125 µM, 24 h) inhibits cell viability against U-251 MG human glioblastoma cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

SphK2-IN-1 相关抗体:

Cell Viability Assay[1]

Cell Line: U-251 MG human glioblastoma cells
Concentration: 125 µM
Incubation Time: 24 h
Result: Decreased cell viability by more than 80%.
分子量

518.92

Formula

C23H22ClF3N8O
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

SphK2-IN-1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SphK2-IN-12927429-64-7SphKSphingosine kinaseADP-GloU-251glioblastomacancerinflammationInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-151350
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