2. Cell Cycle/DNA Damage Cytoskeleton
  3. PAK
  4. st-Ht31

st-Ht31 是一种蛋白激酶 A (PKA) 锚定的膜渗透肽抑制剂。st-Ht31 诱导强烈的胆固醇/磷脂流出。st-Ht31 完全逆转泡沫细胞形成并恢复巨噬细胞的代谢健康。

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Custom Peptide Synthesis

st-Ht31 Chemical Structure

st-Ht31 Chemical Structure

CAS No. : 188425-80-1

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规格 是否有货
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st-Ht31 的其他形式现货产品:

Customer Review

Other Forms of st-Ht31:

st-Ht31 相关抗体

Top Publications Citing Use of Products

查看 PAK 亚型特异性产品:

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PAK1 PAK2 PAK3 PAK4 PAK5 PAK6

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

st-Ht31 is a membrane-permeable peptide inhibitor of protein kinase A (PKA) anchoring. st-Ht31 induces robust cholesterol/phospholipid efflux. st-Ht31 completely reverses foam cell formation and restores the metabolic health of macrophage[1][2].

体外研究
(In Vitro)

st-Ht31 (5 μM; 2 h) enhances cholesterol/phospholipid efflux in BHK cells and RAW macrophages[1].
st-Ht31 (10μM; 24 h) reverses foam cell formation and restores metabolic health of macrophage[1].
st-Ht31 (20 μM; 20 min) abolishes the cAMP inhibition of PMA-induced ERK1/2 activation n HEK293T cells[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

st-Ht31 相关抗体:

Western Blot Analysis[2]

Cell Line: HEK293T cells
Concentration: 20 µM
Incubation Time: 20 min
Result: Abolished the cAMP inhibition of PMA-induced ERK1/2 activation.
分子量

2798.32

Formula

C129H217N29O39
CAS 号
Sequence

{N-Stearate}-Asp-Leu-Ile-Glu-Glu-Ala-Ala-Ser-Arg-Ile-Val-Asp-Ala-Val-Ile-Glu-Gln-Val-Lys-Ala-Ala-Gly-Ala-Tyr
Sequence Shortening

{N-Stearate}-DLIEEAASRIVDAVIEQVKAAGAY
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

st-Ht31 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

st-Ht31188425-80-1PAKp21 activated kinasesBHK cellsRAW macrophagescholesterol/phospholipidfoam cellERK1/2Inhibitorinhibitorinhibit

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产品名称：
st-Ht31
目录号：
HY-P2624
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