2. GPCR/G Protein Neuronal Signaling
  3. Adrenergic Receptor
  4. Sulfinalol

Sulfinalol  (Synonyms: 硫氧洛尔；磺苄心定)

目录号: HY-106499
产品使用指南

摩尔计算器

Sulfinalol 是一种具有口服活性的 β-肾上腺素受体 (β-adrenoceptor) 拮抗剂，具有直接的血管扩张活性。

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Sulfinalol Chemical Structure

Sulfinalol Chemical Structure

CAS No. : 66264-77-5

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Sulfinalol 相关抗体

Top Publications Citing Use of Products

查看 Adrenergic Receptor 亚型特异性产品:

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α adrenergic receptor β adrenergic receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Sulfinalol is an orally active β-adrenoceptor antagonist with direct vasodilator activity[1].

IC50 & Target

β-adrenoceptor

 

体内研究
(In Vivo)

Sulfinalol shows direct vasodilator activity and antihypertensive activity[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Mongrel dogs weighing 8.7-21.2 kg were anesthetized with pentobarbital (30-35 mg/kg, i.v., followed by a continuous infusion of 4 mg/kg/h)[1]
Dosage: 0-100 µg
Administration: Intraarterial injection
Result: Increased blood flow in the sympathetically denervated hindlimb of anesthetized dogs.
Animal Model: Male spontaneously hypertensive rats (SHR)[1]
Dosage: 2.5 mg/kg
Administration: Oral administration
Result: Reduced pressure of conscious spontaneously hypertensive rats.
分子量

377.50

Formula

C20H27NO4S
CAS 号
中文名称

硫氧洛尔；磺苄心定
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Sulfinalol 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sulfinalol66264-77-5硫氧洛尔磺苄心定Adrenergic ReceptorBeta ReceptorVasodilator activityOrally activeInhibitorinhibitorinhibit

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