2. Neuronal Signaling
  3. Cholinesterase (ChE)
  4. T14-A24

T14-A24 是一种口服有效的、可逆、竞争性、选择性 AChE 抑制剂 (Ki=22 nM，IC50=6 nM)。T14-A24 具有良好的血脑屏障穿透性、显着的神经保护作用和安全的毒理学特征。

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T14-A24 Chemical Structure

T14-A24 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
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T14-A24 相关抗体

Top Publications Citing Use of Products

查看 Cholinesterase (ChE) 亚型特异性产品:

查看所有亚型
AChE BChE

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

T14-A24 is an orally active, reversible, competitive, and selective AChE inhibitor (Ki=22 nM, IC50=6 nM). T14-A24 has benign BBB penetration, remarkable neuroprotective effect, and safe toxicological profile[1].

IC50 & Target

AChE

22 nM (Ki)

体内研究
(In Vivo)

T14-A24 (10 mg/kg，口服)可改善 Aβ 1-42 诱导的认知障碍，显着预防 Aβ 1-42 毒性对小鼠的影响[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

476.55

Formula

C24H24N6O3S
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

T14-A24 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

T14-A24Cholinesterase (ChE)Inhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-161029
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