2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. TRP Channel
  4. TRPV4-IN-5

TRPV4-IN-5 (Compound 1f) 是一种有效的 TRPV4 抑制剂 (IC50 = 0.46 μM)。TRPV4-IN-5 可显著缓解脂多糖 (HY-D1056) 诱导的小鼠急性肺损伤症状。

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TRPV4-IN-5 Chemical Structure

TRPV4-IN-5 Chemical Structure

CAS No. : 3046390-54-6

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TRPV4-IN-5 相关抗体

Top Publications Citing Use of Products

查看 TRP Channel 亚型特异性产品:

查看所有亚型
TRPC TRPM TRPV TRPA TRPML

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

TRPV4-IN-5 (Compound 1f) is a potent TRPV4 inhibitor (IC50 = 0.46 μM). TRPV4-IN-5 significantly alleviates the symptoms of acute lung injury induced by lipopolysaccharide (HY-D1056) in mice[1].

IC50 & Target

TRPV4

0.46 μM (IC50)

分子量

490.83

Formula

C20H22Cl3N3O3S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

TRPV4-IN-5 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TRPV4-IN-53046390-54-6TRP ChannelTransient receptor potential channelsLipopolysaccharideacute lung injuryInhibitorinhibitorinhibit

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目录号：
HY-162765
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