1. Membrane Transporter/Ion Channel
  2. Sodium Channel
  3. Zorevunersen

Zorevunersen  (Synonyms: STK-001)

目录号: HY-148410
产品使用指南

Zorevunersen (STK-001) 是一种反义寡核苷酸,通过提高 SCN1A mRNA 水平从而增强钠通道 Nav1.1 蛋白的表达。Zorevunersen 用于 Dravet 综合征的研究。

该游离形式化合物不稳定,推荐具有相同生物学活性的稳定盐形式 Zorevunersen sodium

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RNA, (P-thio)[2′-O-(2-methoxyethyl)](A-G-m5U-m5U-G-G-A-G-m5C-A-A-G-A-m5U-m5U-A-m5U-m5C)

Zorevunersen Chemical Structure

CAS No. : 2415330-04-8

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Zorevunersen 的其他形式现货产品:

Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Zorevunersen (STK-001) is an antisense oligonucleotide that is intended to increase the level of productive SCN1A mRNA and consequently increase the expression of the sodium channel Nav1.1 protein. Zorevunersen is used for the study of Dravet syndrome.

IC50 & Target

Nav1.1

 

分子量

6682.39

Formula

C204H263N63O114P20S20

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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目录号:
HY-148410
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