2. GPCR/G Protein Neuronal Signaling
  3. mAChR Adrenergic Receptor
  4. β2AR/M-receptor agonist-1

β2AR/M-receptor agonist-1 (example 131) 是毒蕈碱拮抗剂和 β2 肾上腺素受体激动剂 (MABA)。β2AR/M-receptor agonist-1 对 β2 肾上腺素能受体的 EC50 值为 9.2 nM。β2AR/M-receptor agonist-1 对毒蕈碱受体的 Ki 值为 30.2 nM。β2AR/M-receptor agonist-1 具有 MABA 效能，EC50 值为 4.0 nM。

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β2AR/M-receptor agonist-1 Chemical Structure

β2AR/M-receptor agonist-1 Chemical Structure

CAS No. : 2230520-62-2

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β2AR/M-receptor agonist-1 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

β2AR/M-receptor agonist-1 (example 131) is a muscarinic antagonist and β2 adrenoceptor agonist (MABA). β2AR/M-receptor agonist-1 shows potency to β2 adrenoceptor with an EC50 value of 9.2 nM. β2AR/M-receptor agonist-1 also has potency to muscarinic receptor with a Ki value of 30.2 nM. β2AR/M-receptor agonist-1 shows MABA potency with an EC50 value of 4.0 nM[1].

体内研究
(In Vivo)

β2AR/M-receptor agonist-1 (0.01 和 0.1 mg/kg；静脉注射，一次) 降低比格犬的心率[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

806.82

Formula

C43H56BrN3O7
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

β2AR/M-receptor agonist-1 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

β2AR/M-receptor agonist-12230520-62-2mAChRAdrenergic ReceptorMuscarinic acetylcholine receptorBeta Receptorheart ratedogMABAInhibitorinhibitorinhibit

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