1. Apoptosis Cell Cycle/DNA Damage
  2. CDK Apoptosis
  3. 3-ATA

3-ATA (NSC 680434) 一种选择性细胞周期蛋白依赖性激酶 4 (CDK4) 抑制剂,具有神经保护和抗肿瘤作用。3-ATA 能够减轻红藻氨酸 (HY-N2309) 诱导的小脑颗粒神经元凋亡 (apoptosis),可以用于神经退行性疾病的研究。

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3-ATA Chemical Structure

3-ATA Chemical Structure

CAS No. : 129821-08-5

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  • 生物活性

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生物活性

3-ATA (NSC 680434) is a selective inhibitor of cyclin-dependent kinase 4 (CDK4) with neuroprotective and antitumor effects. 3-ATA can alleviate kainic acid (HY-N2309)-induced apoptosis in cerebellar granule neurons, which can be used in the study of neurodegenerative diseases[1].

分子量

226.30

Formula

C13H10N2S

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
3-ATA
目录号:
HY-133956
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