2. Neuronal Signaling
  3. Cholinesterase (ChE)
  4. 4-Methoxyphenyl isothiocyanate

4-Methoxyphenyl isothiocyanate  (Synonyms: 4-Methylphenyl ITC)

目录号: HY-W540232
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摩尔计算器

4-Methoxyphenyl isothiocyanate (4-Methylphenyl ITC) 是一种抗氧化剂，其对 DPPH 自由基的清除能力表现为 IC50 为 1.25 mM，ORAC 测试显示其抗氧化能力为 11.7 mM TE (表示该化合物的抗氧化效力相当于 11.7 mmol 的 Trolox (HY-101445，一种抗氧化剂标准品) 在同样条件下的效力)，并在 Briggs–Rauscher 反应中延长氧化过程约 9180 秒。同时，4-Methoxyphenyl isothiocyanate 具有一定的胆碱酯酶抑制活性，对乙酰胆碱酯酶 (AChE) 的抑制率为 30.4%，对丁酰胆碱酯酶 (BChE) 的抑制率为 17.9%。4-Methoxyphenyl isothiocyanate 有望用于抗氧化和神经系统疾病领域的研究。

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4-Methoxyphenyl isothiocyanate Chemical Structure

4-Methoxyphenyl isothiocyanate Chemical Structure

CAS No. : 2284-20-0

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4-Methoxyphenyl isothiocyanate 相关抗体

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  • 生物活性

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生物活性

4-Methoxyphenyl isothiocyanate (4-Methylphenyl ITC) is an antioxidant, with a IC50 value of 1.25 mM for scavenging DPPH radicals. ORAC testing indicates its antioxidant capacity as 11.7 mM TE (indicating that the antioxidant efficacy of this compound is equivalent to 11.7 mmol of Trolox (HY-101445, a standard antioxidant) under the same conditions), and it extends the oxidation process by approximately 9180 seconds in the Briggs–Rauscher reaction. Additionally, 4-Methoxyphenyl isothiocyanate exhibits moderate cholinesterase inhibitory activity, with an inhibition rate of 30.4% against acetylcholinesterase (AChE) and 17.9% against butyrylcholinesterase (BChE). 4-Methoxyphenyl isothiocyanate holds potential for research in the fields of antioxidation and neurological disorders[1].

分子量

165.21

Formula

C8H7NOS
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

4-Methoxyphenyl isothiocyanate 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

4-Methoxyphenyl isothiocyanate2284-20-04-Methylphenyl ITCCholinesterase (ChE)Inhibitorinhibitorinhibit

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