2. PI3K/Akt/mTOR NF-κB
  3. Akt NF-κB PI3K
  4. 5,4'-Dihydroxy-6,8-dimethoxy-7-O-rhamnosyl flavone

5,4'-Dihydroxy-6,8-dimethoxy-7-O-rhamnosyl flavone  (Synonyms: DDR)

目录号: HY-N12959
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摩尔计算器

5,4'-Dihydroxy-6,8-dimethoxy-7-O-rhamnosyl flavone (DDR) 是一种抗癌剂，可以从木蓝中提取得到。5,4'-Dihydroxy-6,8-dimethoxy-7-O-rhamnosyl flavone 能够抑制 PI3K/AKT 和 NF-кB 通路，抑制癌细胞的侵袭和迁移，具有抗癌活性。

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5,4'-Dihydroxy-6,8-dimethoxy-7-O-rhamnosyl flavone Chemical Structure

5,4'-Dihydroxy-6,8-dimethoxy-7-O-rhamnosyl flavone Chemical Structure

CAS No. : 927406-46-0

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5,4'-Dihydroxy-6,8-dimethoxy-7-O-rhamnosyl flavone 相关抗体

Top Publications Citing Use of Products

查看 Akt 亚型特异性产品:

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Akt Akt1 Akt2 Akt3

查看 NF-κB 亚型特异性产品:

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NF-κB NF-κB1/p50 RelA/p65 RelB c-Rel

查看 PI3K 亚型特异性产品:

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PI3Kα PI3Kβ PI3Kγ PI3Kδ PI3KC2α PI3KC2β PI3KC2γ Vps34 PI3K PI3KC3 p120γ

  • 生物活性

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  • 参考文献

生物活性

5,4'-Dihydroxy-6,8-dimethoxy-7-O-rhamnosyl flavone (DDR) is an anticancer agent that can be extracted from Indigofera ovata. 5,4'-Dihydroxy-6,8-dimethoxy-7-O-rhamnosyl flavone can inhibit the PI3K/AKT and NF-кB pathways, inhibit the invasion and migration of cancer cells, and has anticancer activity[1].

分子量

476.43

Formula

C23H24O11
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

5,4'-Dihydroxy-6,8-dimethoxy-7-O-rhamnosyl flavone 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

5,4'-Dihydroxy-6,8-dimethoxy-7-O-rhamnosyl flavone927406-46-0DDRAktNF-κBPI3KPKBProtein kinase BNuclear factor-κBNuclear factor-kappaBPhosphoinositide 3-kinaseInhibitorinhibitorinhibit

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