1. Cell Cycle/DNA Damage Anti-infection
  2. Nucleoside Antimetabolite/Analog DNA/RNA Synthesis Bacterial Influenza Virus
  3. 6-Azathymine

6-Azathymine,胸腺嘧啶的 6-氮类似物,是一种有效的 D-3-氨基异丁酸酯-丙酮酸氨基转移酶 (D-3-aminoisobutyrate-pyruvate aminotransferase) 抑制剂。6-Azathymine 可抑制 DNA 的生物合成,并具有抗菌和抗病毒活性。

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6-Azathymine Chemical Structure

6-Azathymine Chemical Structure

CAS No. : 932-53-6

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250 mg ¥950
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500 mg ¥1200
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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

6-Azathymine, a 6-nitrogen analog of thymine, is a potent D-3-aminoisobutyrate-pyruvate aminotransferase inhibitor. 6-Azathymine inhibits the biosynthesis of DNA, and has antibacterial and antiviral activities[1][2][3][4].

体外研究
(In Vitro)

6-Azathymine is a competitive antagonist of the growth of Streptococcus faecalis (8043) and several other strains of microorganisms. Studies of the mechanism of action of 6-Azathymine reveal that S. faecalis can convert the analog to the corresponding deoxyriboside, azathymidine[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

The administration of 6-Azathymine to the mouse leads to the urinary elimination not only of free Azathymine, but also of various metabolites of it. Following the administration of 6-Azathymine-5-14C to mice, radioactivity is found in all tissues investigated, not only in the form of free Azathymine, but also as metabolic derivatives[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

127.10

Formula

C4H5N3O2

CAS 号
性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
细胞实验: 

DMSO 中的溶解度 : 125 mg/mL (983.48 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响,请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 7.8678 mL 39.3391 mL 78.6782 mL
5 mM 1.5736 mL 7.8678 mL 15.7356 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息:

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

由于实验过程有损耗,建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料
参考文献

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 7.8678 mL 39.3391 mL 78.6782 mL 196.6955 mL
5 mM 1.5736 mL 7.8678 mL 15.7356 mL 39.3391 mL
10 mM 0.7868 mL 3.9339 mL 7.8678 mL 19.6696 mL
15 mM 0.5245 mL 2.6226 mL 5.2452 mL 13.1130 mL
20 mM 0.3934 mL 1.9670 mL 3.9339 mL 9.8348 mL
25 mM 0.3147 mL 1.5736 mL 3.1471 mL 7.8678 mL
30 mM 0.2623 mL 1.3113 mL 2.6226 mL 6.5565 mL
40 mM 0.1967 mL 0.9835 mL 1.9670 mL 4.9174 mL
50 mM 0.1574 mL 0.7868 mL 1.5736 mL 3.9339 mL
60 mM 0.1311 mL 0.6557 mL 1.3113 mL 3.2783 mL
80 mM 0.0983 mL 0.4917 mL 0.9835 mL 2.4587 mL
100 mM 0.0787 mL 0.3934 mL 0.7868 mL 1.9670 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
6-Azathymine
目录号:
HY-136559
需求量: