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  3. 9-Amino-6-chloro-2-methoxyacridine

9-Amino-6-chloro-2-methoxyacridine 

目录号: HY-118155 纯度: 99.56%
COA 产品使用指南

9-Amino-6-chloro-2-methoxyacridine 是一种 pH 敏感的荧光探针。9-Amino-6-chloro-2-methoxyacridine 经常用于测量特定底物通过假定的 H+/溶质反转运系统穿过液泡膜时液泡 pH 值的变化。

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9-Amino-6-chloro-2-methoxyacridine Chemical Structure

9-Amino-6-chloro-2-methoxyacridine Chemical Structure

CAS No. : 3548-09-2

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     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 价格 是否有货 数量
10 mM * 1 mL in DMSO ¥770
In-stock
5 mg ¥700
In-stock
10 mg ¥1200
In-stock
25 mg ¥2450
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50 mg   询价  
100 mg   询价  

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

9-Amino-6-chloro-2-methoxyacridine is a pH sensitive fluorescent probe. 9-Amino-6-chloro-2-methoxyacridine has been frequently used to measure changes in vacuolar pH when a specific substrate crosses the tonoplast through a putative H+/solute antiport system[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HT-22 EC50
7.41 μM
Compound: 46
Cytotoxicity against mouse HT22 cells after 24 hrs by MTT assay
Cytotoxicity against mouse HT22 cells after 24 hrs by MTT assay
[PMID: 24602904]
Panel NCI-60 cells GI50
1 μM
Compound: 8
Antiproliferative activity against human Panel NCI-60 (60 carcinoma cell lines) assessed as cell growth inhibition incubated for 48 hrs
Antiproliferative activity against human Panel NCI-60 (60 carcinoma cell lines) assessed as cell growth inhibition incubated for 48 hrs
[PMID: 34731767]
ScN2a EC50
0.13 μM
Compound: 19
Antiprion activity against scrapie prion protein RML infected mouse ScN2a cells assessed as reduction of scrapie prion protein accumulation by immunoblot analysis
Antiprion activity against scrapie prion protein RML infected mouse ScN2a cells assessed as reduction of scrapie prion protein accumulation by immunoblot analysis
[PMID: 18556207]
T98G GI50
0.6 μM
Compound: 8
Antiproliferative activity against human T98G cells assessed as cell growth inhibition incubated for 96 hrs by CellTiter-Glo luminescent cell viability assay
Antiproliferative activity against human T98G cells assessed as cell growth inhibition incubated for 96 hrs by CellTiter-Glo luminescent cell viability assay
[PMID: 34731767]
分子量

258.70

Formula

C14H11ClN2O

CAS 号
性状

固体

颜色

Light yellow to green yellow

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

溶解性数据
细胞实验: 

DMSO 中的溶解度 : 25 mg/mL (96.64 mM; 超声助溶 (<60°C); 吸湿的 DMSO 对产品的溶解度有显著影响,请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 3.8655 mL 19.3274 mL 38.6548 mL
5 mM 0.7731 mL 3.8655 mL 7.7310 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息:

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

由于实验过程有损耗,建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料

纯度: 99.56%

参考文献

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.8655 mL 19.3274 mL 38.6548 mL 96.6370 mL
5 mM 0.7731 mL 3.8655 mL 7.7310 mL 19.3274 mL
10 mM 0.3865 mL 1.9327 mL 3.8655 mL 9.6637 mL
15 mM 0.2577 mL 1.2885 mL 2.5770 mL 6.4425 mL
20 mM 0.1933 mL 0.9664 mL 1.9327 mL 4.8319 mL
25 mM 0.1546 mL 0.7731 mL 1.5462 mL 3.8655 mL
30 mM 0.1288 mL 0.6442 mL 1.2885 mL 3.2212 mL
40 mM 0.0966 mL 0.4832 mL 0.9664 mL 2.4159 mL
50 mM 0.0773 mL 0.3865 mL 0.7731 mL 1.9327 mL
60 mM 0.0644 mL 0.3221 mL 0.6442 mL 1.6106 mL
80 mM 0.0483 mL 0.2416 mL 0.4832 mL 1.2080 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
9-Amino-6-chloro-2-methoxyacridine
目录号:
HY-118155
需求量: