2. Metabolic Enzyme/Protease Apoptosis
  3. NAMPT Apoptosis
  4. STF-118804

STF-118804是烟酰胺磷酸核糖基转移酶NAMPT高选择性抑制剂，对多个 B 细胞系活力的抑制作用的IC50 小于10nM。

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STF-118804 Chemical Structure

STF-118804 Chemical Structure

CAS No. : 894187-61-2

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     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货 数量
10 mM * 1 mL in DMSO ￥660
In-stock
5 mg ￥600
In-stock
10 mg ￥920
In-stock
25 mg ￥1900
In-stock
50 mg ￥3100
In-stock
100 mg ￥4600
In-stock
200 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

Customer Review

STF-118804 相关抗体

Top Publications Citing Use of Products

MCE 顾客使用本产品发表的 1 篇科研文献

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

STF-118804 is a highly specific NAMPT inhibitor; reduces the viability of most B-ALL cell lines with IC50 <10 nM.

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
B-ALL EC50
0.061 μM
Compound: 1
Antiproliferative activity against mouse B-ALL BCR-ABL double knockout cells assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay
Antiproliferative activity against mouse B-ALL BCR-ABL double knockout cells assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay
[PMID: 30611980]
B-ALL EC50
0.072 μM
Compound: 1
Antiproliferative activity against mouse B-ALL cells expressing wild type BCR-ABL assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay
Antiproliferative activity against mouse B-ALL cells expressing wild type BCR-ABL assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay
[PMID: 30611980]
BJ EC50
2.4938 μM
Compound: 1
Antiproliferative activity against human BJ assessed as cell viability after 72 hrs by CellTiter-Glo assay
Antiproliferative activity against human BJ assessed as cell viability after 72 hrs by CellTiter-Glo assay
[PMID: 30611980]
K562 EC50
4.6 μM
Compound: 1
Antiproliferative activity against human K562 assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay
Antiproliferative activity against human K562 assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay
[PMID: 30611980]
KOPN-8 EC50
1.23 μM
Compound: 1
Antiproliferative activity against human KOPN8 assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay
Antiproliferative activity against human KOPN8 assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay
[PMID: 30611980]
MV4-11 EC50
3.8 μM
Compound: 1
Antiproliferative activity against human MV411 assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay
Antiproliferative activity against human MV411 assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay
[PMID: 30611980]
NALM-6 EC50
0.026 μM
Compound: 1
Antiproliferative activity against human NALM6 assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay
Antiproliferative activity against human NALM6 assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay
[PMID: 30611980]
SUP-B15 EC50
1.1 μM
Compound: 1
Antiproliferative activity against human SUP-B15 assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay
Antiproliferative activity against human SUP-B15 assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay
[PMID: 30611980]
UoC-B1 EC50
> 54.98 μM
Compound: 1
Antiproliferative activity against human UOCB1 assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay
Antiproliferative activity against human UOCB1 assessed as reduction in cell viability after 72 hrs by CellTiter-Glo assay
[PMID: 30611980]
分子量

461.53

Formula

C25H23N3O4S
CAS 号
性状

固体

颜色

White to light yellow

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
溶解性数据
细胞实验： 

DMSO 中的溶解度 : 25 mg/mL (54.17 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.1667 mL 10.8335 mL 21.6671 mL
5 mM 0.4333 mL 2.1667 mL 4.3334 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 2 years; -20°C, 1 year。-80°C储存时，请在2年内使用， -20°C储存时，请在1年内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料

纯度: 99.72%

COA (287 KB) HNMR (277 KB) LCMS (94 KB)

产品使用指南 (1538 KB)
参考文献

STF-118804 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 2 years; -20°C, 1 year。-80°C储存时，请在2年内使用， -20°C储存时，请在1年内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.1667 mL 10.8335 mL 21.6671 mL 54.1677 mL
5 mM 0.4333 mL 2.1667 mL 4.3334 mL 10.8335 mL
10 mM 0.2167 mL 1.0834 mL 2.1667 mL 5.4168 mL
15 mM 0.1444 mL 0.7222 mL 1.4445 mL 3.6112 mL
20 mM 0.1083 mL 0.5417 mL 1.0834 mL 2.7084 mL
25 mM 0.0867 mL 0.4333 mL 0.8667 mL 2.1667 mL
30 mM 0.0722 mL 0.3611 mL 0.7222 mL 1.8056 mL
40 mM 0.0542 mL 0.2708 mL 0.5417 mL 1.3542 mL
50 mM 0.0433 mL 0.2167 mL 0.4333 mL 1.0834 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

STF-118804894187-61-2STF118804STF 118804NAMPTApoptosisNicotinamide phosphoribosyl transferasePBEFVisfatinpre-B cell-enhancing factorPre-B cell colony enhancing factorInhibitorinhibitorinhibit

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产品名称：
STF-118804
目录号：
HY-12808
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