2. Anti-infection
  3. Bacterial
  4. Squalamine lactate

Squalamine lactate  (Synonyms: MSI-1256F)

目录号: HY-16467 纯度: 98.27%
COA 产品使用指南

摩尔计算器

Squalamine lactate 是一种从角鲨体内分到的氨基甾醇，具有抗菌活性，同时可用于新生血管性年龄相关性黄斑变性的研究。

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Squalamine lactate Chemical Structure

Squalamine lactate Chemical Structure

CAS No. : 320725-47-1

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规格 价格 是否有货 数量
1 mg ￥4500
In-stock
5 mg 现货 询价
10 mg   询价  
50 mg   询价  

* Please select Quantity before adding items.

Customer Review

Other Forms of Squalamine lactate:

Squalamine lactate 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Squalamine lactate is an aminosterol compound discovered in the tissues of the dogfish shark, with antimicrobial activity, and used for the treatment of neovascular age-related macular degeneration.

体外研究
(In Vitro)

Squalamine lactate has a more generalized effect on the cellular signaling cascade that is common to both VEGF and other growth factors[1]. Squalamine blocks the action of VEGF and integrin expression, thereby inhibiting angiogenesis, when bound to calmodulin[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Squalamine lactate 相关抗体:
体内研究
(In Vivo)

Squalamine is ineffective when administered intravitreally and therefore requires intravenous dosing. However, systemic dosing has yielded promising results in rats as well as humans[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
分子量

718.04

Formula

C37H71N3O8S
CAS 号
性状

固体

颜色

Light yellow to yellow

结构分类
初始来源

Squalus acanthias
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶解性数据
细胞实验： 

DMSO 中的溶解度 : ≥ 36.66 mg/mL (51.06 mM; 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO)

* "≥" means soluble, but saturation unknown.

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.3927 mL 6.9634 mL 13.9268 mL
5 mM 0.2785 mL 1.3927 mL 2.7854 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料
参考文献

Squalamine lactate 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.3927 mL 6.9634 mL 13.9268 mL 34.8170 mL
5 mM 0.2785 mL 1.3927 mL 2.7854 mL 6.9634 mL
10 mM 0.1393 mL 0.6963 mL 1.3927 mL 3.4817 mL
15 mM 0.0928 mL 0.4642 mL 0.9285 mL 2.3211 mL
20 mM 0.0696 mL 0.3482 mL 0.6963 mL 1.7409 mL
25 mM 0.0557 mL 0.2785 mL 0.5571 mL 1.3927 mL
30 mM 0.0464 mL 0.2321 mL 0.4642 mL 1.1606 mL
40 mM 0.0348 mL 0.1741 mL 0.3482 mL 0.8704 mL
50 mM 0.0279 mL 0.1393 mL 0.2785 mL 0.6963 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Squalamine320725-47-1MSI-1256FBacterialInhibitorinhibitorinhibit

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目录号：
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