2. Signaling Pathways
  3. VISTA

VISTA (V-domain 免疫球蛋白 T 细胞活化抑制因子 (VISTA))

V-domain Ig suppressor of T cell activation (VISTA)

V-domain immunoglobulin suppressor of T cell activation (VISTA) is a novel inhibitory immune checkpoints (ICs) that is expressed on myeloid cells, lymphoid cells, and tumoral cells; therefore, VISTA can substantially regulate innate and

adaptive anti-tumoral immune responses. VISTA is a transmembrane protein that plays a crucial role in the regulation of antitumor immunity. Therapeutic intervention that inhibits the VISTA pathway constitutes a new approach in the treatment of cancer.

VISTA 相关产品 (1):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-Q25865
    MG-V-53 Inhibitor
    MG-V-53 是一种有效的小分子 V 结构域的 T 细胞活化免疫球蛋白抑制因子 (VISTA) 抑制剂，IC50 值为 121 nM。MG-V-53 具有抗肿瘤活性。
    MG-V-53
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