2. Neuronal Signaling
  3. Monoamine Oxidase Cholinesterase (ChE)
  4. AChE/BChE/MAO-B-IN-3

AChE/BChE/MAO-B-IN-3 是一种 1-茚满酮衍生物，是一种有效的 MAO-B 抑制剂，对人 MAO-B 的 IC50 为 0.0359 μM。AChE/BChE/MAO-B-IN-3 是一种有效的 AChE 和 BChE 酶抑制剂，对人 AChE 和 BChE 酶的 IC50 值分别为 0.0473 μM 和 0.0782 μM。AChE/BChE/MAO-B-IN-3 显示出显着的抗氧化活性，并具有用于阿尔茨海默病 (AD) 研究的潜力。

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AChE/BChE/MAO-B-IN-3 Chemical Structure

AChE/BChE/MAO-B-IN-3 Chemical Structure

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AChE/BChE/MAO-B-IN-3 相关抗体

Top Publications Citing Use of Products

查看 Monoamine Oxidase 亚型特异性产品:

查看所有亚型
MAO-A MAO-B

查看 Cholinesterase (ChE) 亚型特异性产品:

查看所有亚型
AChE BChE

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

AChE/BChE/MAO-B-IN-3, an indan-1-one derivative, is a potent MAO-B inhibitor with an IC50 of 0.0359 μM for human MAO-B. AChE/BChE/MAO-B-IN-3 is a potent AChE and BChE enzyme inhibitor, with IC50s of 0.0473 μM and 0.0782 μM for human AChE and BChE enzyme, respectively. AChE/BChE/MAO-B-IN-3 shows significant antioxidant activity and has the potential for Alzheimer's disease (AD) research[1].

IC50 & Target[1]

hMAO-B

0.0359 μM (IC50)

hAChE

0.0473 μM (IC50)

hBCHE

0.0782 μM (IC50)

体外研究
(In Vitro)

AChE/BChE/MAO-B-IN-3 (compound D38) 对 NIH/3T3 成纤维细胞系的 IC50 值为 6.8118 μM[1]。
AChE/BChE/MAO-B-IN-3 (1 mM) 表现出对人 AChE 和 BChE 酶的强抑制特性，均产生 93% 的活性抑制[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

AChE/BChE/MAO-B-IN-3 相关抗体:
分子量

421.53

Formula

C25H31N3O3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

AChE/BChE/MAO-B-IN-3 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AChE/BChE/MAO-B-IN-3Monoamine OxidaseCholinesterase (ChE)MAOindan-1-oneMAO-BAChEBChEantioxidant,?Alzheimer's disease ,ADInhibitorinhibitorinhibit

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