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  2. Isotope-Labeled Compounds
  3. Aflatoxin B1-13C17

Aflatoxin B1-13C17  (Synonyms: 黄曲霉毒素B1-13C17)

目录号: HY-N6615S 纯度: 99.90%
COA 产品使用指南 技术支持

Aflatoxin B1-13C17 是一种 13C 标记的 Aflatoxin B1 (HY-N6615)。Aflatoxin B1 (AFB1) 是一种 1A 类致癌物质,是由 Aspergillus flavusA. parasiticus 产生的次级代谢产物。Aflatoxin B1 主要通过在抑癌基因 p53 的密码子 249 的第三位引发 G 到 T 的转换,从而导致突变。在体内,Aflatoxin B1 可引起肠道和肾脏损伤,并具有一定的致畸作用。

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Aflatoxin B1-<sup>13</sup>C<sub>17</sub> Chemical Structure

Aflatoxin B1-13C17 Chemical Structure

CAS No. : 1217449-45-0

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规格 价格 是否有货 数量
0.6 μg (1.51 μM * 1.2 mL in Acetonitrile) ¥11000
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Other Forms of Aflatoxin B1-13C17:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Aflatoxin B1-13C17 is 13C- and 15N-labeled Aflatoxin B1 (HY-N6615). Aflatoxin B1 (AFB1) is a Group 1A carcinogen and a secondary metabolite produced by Aspergillus flavus and Aspergillus parasiticus. Aflatoxin B1 (AFB1) primarily induces mutations by causing a G to T transversion at the third nucleotide of codon 249 in the tumor suppressor gene p53. In the body, Aflatoxin B1 (AFB1) can cause damage to the intestines and kidneys and has some teratogenic effects[1].

体外研究
(In Vitro)

氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

329.15

Formula

13C17H12O6

CAS 号
非标记 CAS
性状

液体

颜色

Colorless to light yellow

中文名称

黄曲霉毒素B1-13C17

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料

纯度: 99.90%

参考文献
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  • 稀释计算器

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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