2. Neuronal Signaling
  3. Cholinesterase (ChE)
  4. BChE-IN-15

BChE-IN-15 (Compound 6) 是一种伪不可逆、共价 BChE 抑制剂，对 hBChE 的 IC50 为 1.76 nM。

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BChE-IN-15 Chemical Structure

BChE-IN-15 Chemical Structure

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BChE-IN-15 相关抗体

Top Publications Citing Use of Products

查看 Cholinesterase (ChE) 亚型特异性产品:

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AChE BChE

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

BChE-IN-15 (Compound 6) is a pseudo-irreversible and covalent BChE inhibitor with an IC50 of 1.76 nM against hBChE [1].

IC50 & Target[1]

hBCHE

1.76 nM (IC50)

hAChE

558.6 nM (IC50)

体外研究
(In Vitro)

BChE-IN-15 (Compound 6) (0.5-50 μM; 48 h) 显示对 SH-SY5Y 和 HepG2 细胞的细胞毒性[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

BChE-IN-15 相关抗体:

Cell Cytotoxicity Assay[1]

Cell Line: SH-SY5Y and HepG2 cell lines
Concentration: 0.5-50 μM
Incubation Time: 48 h
Result: Showed cytotoxicity with IC50s of 5.8 μM and 7.1 μM against SH-SY5Y and HepG2 cells, respectively.
分子量

371.52

Formula

C22H33N3O2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

BChE-IN-15 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BChE-IN-15Cholinesterase (ChE)SH-SY5YHepG2Inhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-152232
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