2. Neuronal Signaling
  3. Cholinesterase (ChE)
  4. BChE-IN-7

BChE-IN-7 (化合物 13) 是一种有效的、选择性、透过血脑屏障的且可逆的 AChE 和 BChE 抑制剂，其 IC50 为 0.06 μM (BChE)。BChE-IN-7 能保护神经元样细胞免受毒性 Aβ 物种的侵害。

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BChE-IN-7 Chemical Structure

BChE-IN-7 Chemical Structure

CAS No. : 2416910-85-3

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BChE-IN-7 相关抗体

Top Publications Citing Use of Products

查看 Cholinesterase (ChE) 亚型特异性产品:

查看所有亚型
AChE BChE

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

BChE-IN-7 (compound 13) is a potent, selective, BBB-penetrated and reversible AChE and BChE inhibitor, with an IC50 of 0.06 μM (BChE). BChE-IN-7 can protect neuronal-like cells from toxic Aβ-species[1].

IC50 & Target

IC50: 0.06 μM (BChE)[1]
分子量

336.43

Formula

C21H24N2O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

BChE-IN-7 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BChE-IN-72416910-85-3Cholinesterase (ChE)SH-SY5Y cellsHepG2 cellsneuroprotectiveblood-brain barrier permeationAlzheimer’s diseaseMonoamine oxidaseMulti-target-directed ligandsN-Alkylpiperidine carbamatesInhibitorinhibitorinhibit

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目录号：
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